Application of hydrophilic polymers for the preparation of tadalafil solid dispersions: micromeritics properties, release and erectile dysfunction studies in male rats

The objective of the present study was to improve the dissolution rate and aphrodisiac activity of tadalafil by using hydrophilic polymers. Solid dispersions were prepared by solvent evaporation-Rota evaporator using Koliphore 188, Kollidon(®) VA64, and Kollidon(®) 30 polymers in a 1:1 ratio. Prepar...

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Detalles Bibliográficos
Autores principales: Ahmed, Mohammed Muqtader, Anwer, Md Khalid, Soliman, Gamal A., Aldawsari, Mohammed F., Mohammed, Abdul Aleem, Alshehri, Sultan, Ghoneim, Mohammed M., Alali, Amer S., Alshetaili, Abdullah, Alalaiwe, Ahmed, Bukhari, Sarah I., Zafar, Ameeduzzafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Drugs and Devices
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148559/
https://www.ncbi.nlm.nih.gov/pubmed/35642201
http://dx.doi.org/10.7717/peerj.13482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148559/
https://www.ncbi.nlm.nih.gov/pubmed/35642201
http://dx.doi.org/10.7717/peerj.13482

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