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The WNT7A/WNT7B/GPR124/RECK signaling module plays an essential role in mammalian limb development

In central nervous system vascular endothelial cells, signaling via the partially redundant ligands WNT7A and WNT7B requires two co-activator proteins, GPR124 and RECK. WNT7A and RECK have been shown previously to play a role in limb development, but the mechanism of RECK action in this context is u...

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Detalles Bibliográficos
Autores principales: Wang, Yanshu, Venkatesh, Arjun, Xu, Jiajia, Xu, Mingxin, Williams, John, Smallwood, Philip M., James, Aaron, Nathans, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148564/
https://www.ncbi.nlm.nih.gov/pubmed/35552394
http://dx.doi.org/10.1242/dev.200340