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Reduced Osteogenic Differentiation Potential In Vivo in Acute Myeloid Leukaemia Patients Correlates with Decreased BMP4 Expression in Mesenchymal Stromal Cells

The osteogenic differentiation potential of mesenchymal stromal cells (hMSCs) is an essential process for the haematopoiesis and the maintenance of haematopoietic stem cells (HSCs). Therefore, the aim of this work was to evaluate this potential in hMSCs from AML patients (hMSCs-AML) and whether it i...

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Detalles Bibliográficos
Autores principales: Azevedo, Pedro L., Dias, Rhayra B., Nogueira, Liebert P., Maradei, Simone, Bigni, Ricardo, Aragao, Jordana S. R., Abdelhay, Eliana, Binato, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148835/
https://www.ncbi.nlm.nih.gov/pubmed/34966001
http://dx.doi.org/10.15283/ijsc21138