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Increased Tacrolimus Exposure in Kidney Transplant Recipients With COVID-19: Inflammation-Driven Downregulation of Metabolism as a Potential Mechanism

Kidney transplant recipients (KTRs) are at increased risk of severe COVID-19 disease compared to the general population. This is partly driven by their use of immunosuppressive therapy, which influences inflammatory responses and viral loads. Current guidelines suggest to withdraw mycophenolate whil...

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Detalles Bibliográficos
Autores principales: Klomp, Sylvia D., Meziyerh, Soufian, Vissers, Maurits F. J. M., Moes, Dirk J. A. R., Arends, Eline J., Teng, Y. K. Onno, Swen, Jesse J., de Vries, Aiko P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148963/
https://www.ncbi.nlm.nih.gov/pubmed/35651879
http://dx.doi.org/10.3389/ti.2022.10269