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Based on Network Pharmacology and Gut Microbiota Analysis to Investigate the Mechanism of the Laxative Effect of Pterostilbene on Loperamide-Induced Slow Transit Constipation in Mice

Background: Pterostilbene (PTE) is a natural polyphenol compound that has been proven to improve intestinal inflammation, but its laxative effect on slow transit constipation (STC) has never been studied. This study aims to investigate the laxative effect of PTE on loperamide (LOP)-induced STC mice...

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Detalles Bibliográficos
Autores principales: Yao, Zhiwei, Fu, Siqi, Ren, Bingbing, Ma, Lushun, Sun, Daqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148975/
https://www.ncbi.nlm.nih.gov/pubmed/35652049
http://dx.doi.org/10.3389/fphar.2022.913420