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Co-Expression of TIGIT and Helios Marks Immunosenescent CD8(+) T Cells During Aging

Aging leads to alterations in the immune system that result in ineffective responsiveness against pathogens. Features of this process, collectively known as immunosenescence, accumulate in CD8(+) T cells with age and have been ascribed to differentiation of these cells during the course of life. Her...

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Detalles Bibliográficos
Autores principales: Pieren, Daan K. J., Smits, Noortje A. M., Postel, Rimke J., Kandiah, Vinitha, de Wit, Jelle, van Beek, Josine, van Baarle, Debbie, Guichelaar, Teun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9148977/
https://www.ncbi.nlm.nih.gov/pubmed/35651622
http://dx.doi.org/10.3389/fimmu.2022.833531