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Lipid nanoparticle delivery of unmodified mRNAs encoding multiple monoclonal antibodies targeting poxviruses in rabbits

Poxviruses are a large and complex family of viruses with members such as monkeypox virus and variola virus. The possibility of an outbreak of monkeypox virus (or a related poxvirus) or the misuse of variola virus justifies the development of countermeasures. Furthermore, poxviruses can be a useful...

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Detalles Bibliográficos
Autores principales: Mucker, Eric M., Thiele-Suess, Carolin, Baumhof, Patrick, Hooper, Jay W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149018/
https://www.ncbi.nlm.nih.gov/pubmed/35664703
http://dx.doi.org/10.1016/j.omtn.2022.05.025