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Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses

How immune dysregulation affects recovery from COVID-19 infection in patients with cancer remains unclear. We analyzed cellular and humoral immune responses in 103 patients with prior COVID-19 infection, more than 20% of whom had delayed viral clearance. Delayed clearance was associated with loss of...

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Detalles Bibliográficos
Autores principales: Lyudovyk, Olga, Kim, Justin Y., Qualls, David, Hwee, Madeline A., Lin, Ya-Hui, Boutemine, Sawsan R., Elhanati, Yuval, Solovyov, Alexander, Douglas, Melanie, Chen, Eunise, Babady, N. Esther, Ramanathan, Lakshmi, Vedantam, Pallavi, Bandlamudi, Chaitanya, Gouma, Sigrid, Wong, Philip, Hensley, Scott E., Greenbaum, Benjamin, Huang, Alexander C., Vardhana, Santosha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149241/
https://www.ncbi.nlm.nih.gov/pubmed/35679859
http://dx.doi.org/10.1016/j.ccell.2022.05.013