Agonist-Promoted Phosphorylation and Internalization of the Kappa Opioid Receptor in Mouse Brains: Lack of Connection With Conditioned Place Aversion

Selective kappa opioid receptor (KOR) agonists are promising antipruritic agents and analgesics. However, clinical development of KOR agonists has been limited by side effects, including psychotomimetic effects, dysphoria, and sedation, except for nalfurafine, and recently. CR845 (difelikefalin). Ac...

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Detalles Bibliográficos
Autores principales: Chen, Chongguang, Huang, Peng, Bland, Kathryn, Li, Mengchu, Zhang, Yan, Liu-Chen, Lee-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149264/
https://www.ncbi.nlm.nih.gov/pubmed/35652052
http://dx.doi.org/10.3389/fphar.2022.835809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149264/
https://www.ncbi.nlm.nih.gov/pubmed/35652052
http://dx.doi.org/10.3389/fphar.2022.835809

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