Neurons and Astrocytes Elicit Brain Region Specific Transcriptional Responses to Prion Disease in the Murine CA1 and Thalamus

Progressive dysfunction and loss of neurons ultimately culminates in the symptoms and eventual fatality of prion disease, yet the pathways and mechanisms that lead to neuronal degeneration remain elusive. Here, we used RNAseq to profile transcriptional changes in microdissected CA1 and thalamus brai...

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Detalles Bibliográficos
Autores principales: Slota, Jessy A., Medina, Sarah J., Frost, Kathy L., Booth, Stephanie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149297/
https://www.ncbi.nlm.nih.gov/pubmed/35651626
http://dx.doi.org/10.3389/fnins.2022.918811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149297/
https://www.ncbi.nlm.nih.gov/pubmed/35651626
http://dx.doi.org/10.3389/fnins.2022.918811

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