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Reduction of oocyte lipid droplets and meiotic failure due to biotin deficiency was not rescued by restoring the biotin nutritional status

BACKGROUND/OBJECTIVES: Oocyte lipid droplets play a crucial role in meiosis and embryo development. Biotin is associated with fatty acid synthesis and is the coenzyme for acetyl-CoA carboxylase (ACC). The effects of a biotin deficiency on the oocyte lipid metabolism remain unknown. This study examin...

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Detalles Bibliográficos
Autores principales: Tsuji, Ai, Ikeda, Yuka, Murakami, Mutsumi, Kitagishi, Yasuko, Matsuda, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Nutrition Society and the Korean Society of Community Nutrition 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149319/
https://www.ncbi.nlm.nih.gov/pubmed/35663441
http://dx.doi.org/10.4162/nrp.2022.16.3.314