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Extrafollicular Plasmablasts Present in the Acute Phase of Infections Express High Levels of PD-L1 and Are Able to Limit T Cell Response

During infections with protozoan parasites or some viruses, T cell immunosuppression is generated simultaneously with a high B cell activation. It has been described that, as well as producing antibodies, plasmablasts, the differentiation product of activated B cells, can condition the development o...

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Detalles Bibliográficos
Autores principales: Serrán, Melisa Gorosito, Vernengo, Facundo Fiocca, Almada, Laura, Beccaria, Cristian G., Gazzoni, Yamila, Canete, Pablo F., Roco, Jonathan A., Boari, Jimena Tosello, Ramello, Maria Cecilia, Wehrens, Ellen, Cai, Yeping, Zuniga, Elina I., Montes, Carolina L., Cockburn, Ian A., Rodriguez, Eva V. Acosta, Vinuesa, Carola G., Gruppi, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149371/
https://www.ncbi.nlm.nih.gov/pubmed/35651611
http://dx.doi.org/10.3389/fimmu.2022.828734