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Switch Tandem Repeats Influence the Choice of the Alternative End-Joining Pathway in Immunoglobulin Class Switch Recombination

Immunoglobulin class switch recombination (CSR) plays an important role in humoral imm\une responses by changing the effector functions of antibodies. CSR occurs between highly repetitive switch (S) sequences located upstream of immunoglobulin constant gene exons. Switch sequences differ in size, th...

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Detalles Bibliográficos
Autores principales: Oudinet, Chloé, Zhang, Xuefei, Puget, Nadine, Kyritsis, Nia, Leduc, Claire, Braikia, Fatima-Zohra, Dauba, Audrey, Alt, Frederick W., Khamlichi, Ahmed Amine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149575/
https://www.ncbi.nlm.nih.gov/pubmed/35651614
http://dx.doi.org/10.3389/fimmu.2022.870933