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1,25OH-Vitamin D3 and IL-17 Inhibition Modulate Pro-Fibrotic Cytokines Production in Peripheral Blood Mononuclear Cells of Patients with Systemic Sclerosis

Objectives: IL-17 modulates the synthesis of several molecules involved in the pathogenesis of Systemic Sclerosis (SSc). Vitamin D (1,25(OH)(2)D3) shows anti-fibrotic properties and it is able to affect the IL-17 production in several experimental conditions. The aim of this study is to assess the p...

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Detalles Bibliográficos
Autores principales: Corrado, Addolorata, Rotondo, Cinzia, Sanpaolo, Eliana Rita, Altomare, Alberto, Maruotti, Nicola, Cici, Daniela, Cantatore, Francesco Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149638/
https://www.ncbi.nlm.nih.gov/pubmed/35693738
http://dx.doi.org/10.7150/ijms.70984