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Isoforms of Neuropilin-2 Denote Unique Tumor-Associated Macrophages in Breast Cancer

Tumor-associated macrophages (TAMs) exert profound influence over breast cancer progression, promoting immunosuppression, angiogenesis, and metastasis. Neuropilin-2 (NRP2), consisting of the NRP2a and NRP2b isoforms, is a co-receptor for heparin-binding growth factors including VEGF-C and Class 3 Se...

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Detalles Bibliográficos
Autores principales: Dhupar, Rajeev, Jones, Katherine E., Powers, Amy A., Eisenberg, Seth H., Ding, Kai, Chen, Fangyuan, Nasarre, Cecile, Cen, Zhanpeng, Gong, Yi-Nan, LaRue, Amanda C., Yeh, Elizabeth S., Luketich, James D., Lee, Adrian V., Oesterreich, Steffi, Lotze, Michael T., Gemmill, Robert M., Soloff, Adam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149656/
https://www.ncbi.nlm.nih.gov/pubmed/35651620
http://dx.doi.org/10.3389/fimmu.2022.830169