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Pax3 Hypomorphs Reveal Hidden Pax7 Functional Genetic Compensation in Utero

Pax3 and Pax7 transcription factors are paralogs within the Pax gene family that that are expressed in early embryos in partially overlapping expression domains and have distinct functions. Significantly, mammalian development is largely unaffected by Pax7 systemic deletion but systemic Pax3 deletio...

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Detalles Bibliográficos
Autores principales: Zhou, Hong-Ming, Conway, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9149870/
https://www.ncbi.nlm.nih.gov/pubmed/35645295
http://dx.doi.org/10.3390/jdb10020019