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Mammalian Display Platform for the Maturation of Bispecific TCR-Based Molecules

Bispecific T cell receptor (TCR)-based molecules capable of redirecting and activating T cells towards tumor cells represent a novel and promising class of biotherapeutics for the treatment of cancer. Usage of TCRs allows for targeting of intracellularly expressed and highly selective cancer antigen...

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Detalles Bibliográficos
Autores principales: Dilchert, Janine, Hofmann, Martin, Unverdorben, Felix, Kontermann, Roland, Bunk, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150015/
https://www.ncbi.nlm.nih.gov/pubmed/35645207
http://dx.doi.org/10.3390/antib11020034