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Dysregulated cortical synaptic plasticity under methyl-CpG binding protein 2 deficiency and its implication in motor impairments

Caused by the mutation of methyl-CpG binding protein 2 (MeCP2), Rett syndrome leads to a battery of severe neural dysfunctions including the regression of motor coordination and motor learning. Current understanding has revealed the motor cortex as the critical region mediating voluntary movement. I...

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Detalles Bibliográficos
Autores principales: Zhang, Wei-Jia, Shi, Ling-Ling, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150038/
https://www.ncbi.nlm.nih.gov/pubmed/35663301
http://dx.doi.org/10.5498/wjp.v12.i5.673