VEGF signalling causes stalls in brain capillaries and reduces cerebral blood flow in Alzheimer’s mice

Increased incidence of stalled capillary blood flow caused by adhesion of leucocytes to the brain microvascular endothelium leads to a 17% reduction of cerebral blood flow and exacerbates short-term memory loss in multiple mouse models of Alzheimer’s disease. Here, we report that vascular endothelia...

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Detalles Bibliográficos
Autores principales: Ali, Muhammad, Falkenhain, Kaja, Njiru, Brendah N, Murtaza-Ali, Muhammad, Ruiz-Uribe, Nancy E, Haft-Javaherian, Mohammad, Catchers, Stall, Nishimura, Nozomi, Schaffer, Chris B, Bracko, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150081/
https://www.ncbi.nlm.nih.gov/pubmed/35048960
http://dx.doi.org/10.1093/brain/awab387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150081/
https://www.ncbi.nlm.nih.gov/pubmed/35048960
http://dx.doi.org/10.1093/brain/awab387

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