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AMP-activated protein kinase promotes breast cancer stemness and drug resistance

Breast cancer stem cells (BCSCs) are a major cause of therapy resistance and tumour progression. Currently, their regulation is not entirely understood. Previous work from our laboratory demonstrated a context-specific pro-tumorigenic role for AMP-activated protein kinase (AMPK) under anchorage-depr...

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Detalles Bibliográficos
Autores principales: Andugulapati, Sai Balaji, Sundararaman, Ananthalakshmy, Lahiry, Mohini, Rangarajan, Annapoorni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150117/
https://www.ncbi.nlm.nih.gov/pubmed/35195687
http://dx.doi.org/10.1242/dmm.049203