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Effect of alcohol coadministration on the pharmacodynamics, pharmacokinetics, and safety of lemborexant: A randomized, placebo-controlled crossover study

BACKGROUND: Lemborexant is a dual orexin receptor antagonist approved to treat insomnia in adults in several countries including the USA, Canada, and Japan. AIMS: This study was conducted to investigate effects of lemborexant and alcohol coadministration on postural stability, cognitive performance,...

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Detalles Bibliográficos
Autores principales: Landry, Ishani, Hall, Nancy, Aluri, Jagadeesh, Filippov, Gleb, Setnik, Beatrice, Dayal, Satish, Reyderman, Larisa, Moline, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150140/
https://www.ncbi.nlm.nih.gov/pubmed/35634694
http://dx.doi.org/10.1177/02698811221080459