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TGF-β1 regulates chondrocyte proliferation and extracellular matrix synthesis via circPhf21a-Vegfa axis in osteoarthritis

BACKGROUND: The transforming growth factor-beta (TGF-β) signaling pathway is an important pathway associated with the pathogenesis of osteoarthritis (OA). This study was to investigate the involvement of circRNAs in the TGF-β signaling pathway. METHODS: Cell Counting Kit-8 (CCK-8) assay and 5-ethyny...

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Detalles Bibliográficos
Autores principales: Lin, Shiyuan, Li, Huizi, Wu, Biao, Shang, Jie, Jiang, Ning, Peng, Rong, Xing, Baizhou, Xu, Xianghe, Lu, Huading
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150374/
https://www.ncbi.nlm.nih.gov/pubmed/35637489
http://dx.doi.org/10.1186/s12964-022-00881-9