Anticancer mechanism of 7-α-hydroxyfrullanolide on microtubules and computational prediction of its target binding in triple-negative breast cancer cells

BACKGROUND: Triple-negative breast cancer (TNBC) responds poorly to the available drugs; thus, the mortality rate associated with TNBC remains high. 7-α-Hydroxyfrullanolide (7HF) possesses anticancer properties and arrests cells in the G2/M-phase via modulation of several proteins involved in the G2...

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Detalles Bibliográficos
Autores principales: Chimplee, Siriphorn, Smythe, Carl, Tipmanee, Varomyalin, Sukrong, Suchada, Kanokwiroon, Kanyanatt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150694/
https://www.ncbi.nlm.nih.gov/pubmed/35651747
http://dx.doi.org/10.7717/peerj.13508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150694/
https://www.ncbi.nlm.nih.gov/pubmed/35651747
http://dx.doi.org/10.7717/peerj.13508

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