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Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line

OBJECTIVE(S): Humic acid (HA) and Fulvic acid (FA) are major members of humic substances, which are extracted from organic sources including soil and peat. The pro-apoptotic and anti-melanogenic effects of HA and FA at the cellular and molecular levels in the A375 human melanoma cell line were exami...

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Detalles Bibliográficos
Autores principales: Salehi, Mitra, Piri, Hossein, Farasat, Alireza, Pakbin, Babak, Gheibi, Nematollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150800/
https://www.ncbi.nlm.nih.gov/pubmed/35656077
http://dx.doi.org/10.22038/IJBMS.2022.60651.13444