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Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection

OBJECTIVE(S): Methicillin-resistant Staphylococcus aureus (MRSA) reasons extreme infections, can resist various conventional antimicrobial agents, and cause morbidity and mortality worldwide. Vaccination seems to help modulate MRSA infections. Nanovaccine is considered a novel strategy in vaccine te...

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Detalles Bibliográficos
Autores principales: Haghighat, Setareh, Siadat, Seyed Davar, Akhavan Sepahi, Abbas, Mahdavi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150805/
https://www.ncbi.nlm.nih.gov/pubmed/35656080
http://dx.doi.org/10.22038/IJBMS.2022.59992.13303