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Accumulation of Lipid Droplets in a Novel Bietti Crystalline Dystrophy Zebrafish Model With Impaired PPARα Pathway

PURPOSE: Bietti crystalline dystrophy (BCD) is a progressive retinal degenerative disease primarily characterized by numerous crystal-like deposits and degeneration of retinal pigment epithelium (RPE) and photoreceptor cells. CYP4V2 (cytochrome P450 family 4 subfamily V member 2) is currently the on...

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Detalles Bibliográficos
Autores principales: Gao, Pan, Jia, Danna, Li, Pei, Huang, Yuwen, Hu, Hualei, Sun, Kui, Lv, Yuexia, Chen, Xiang, Han, Yunqiao, Zhang, Zuxiao, Ren, Xiang, Wang, Qing, Liu, Fei, Tang, Zhaohui, Liu, Mugen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150832/
https://www.ncbi.nlm.nih.gov/pubmed/35616930
http://dx.doi.org/10.1167/iovs.63.5.32