Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4(+) T Cell Activities via Direct Binding With Cytochrome P450 1B1

Astilbin, as a compound of flavonoids, exerts anti-inflammation, antioxidation, and immune-suppression activities. Decreased activation of NF-κB and p38 MAPK and increased activation of SOCS3 and AMPK have been found in astilbin-treated cells. However, what molecules are docked by astilbin to initia...

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Detalles Bibliográficos
Autores principales: Ding, Shizhen, Lu, Guotao, Wang, Biying, Xiang, Jie, Hu, Chunxia, Lin, Zhijie, Ding, Yanbing, Xiao, Weiming, Gong, Weijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150850/
https://www.ncbi.nlm.nih.gov/pubmed/35652039
http://dx.doi.org/10.3389/fphar.2022.848957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150850/
https://www.ncbi.nlm.nih.gov/pubmed/35652039
http://dx.doi.org/10.3389/fphar.2022.848957

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