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Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4(+) T Cell Activities via Direct Binding With Cytochrome P450 1B1
Astilbin, as a compound of flavonoids, exerts anti-inflammation, antioxidation, and immune-suppression activities. Decreased activation of NF-κB and p38 MAPK and increased activation of SOCS3 and AMPK have been found in astilbin-treated cells. However, what molecules are docked by astilbin to initia...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150850/ https://www.ncbi.nlm.nih.gov/pubmed/35652039 http://dx.doi.org/10.3389/fphar.2022.848957 |