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Genomic determinants of Furin cleavage in diverse European SARS-related bat coronaviruses

The furin cleavage site (FCS) in SARS-CoV-2 is unique within the Severe acute respiratory syndrome–related coronavirus (SrC) species. We re-assessed diverse SrC from European horseshoe bats and analyzed the spike-encoding genomic region harboring the FCS in SARS-CoV-2. We reveal molecular features i...

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Detalles Bibliográficos
Autores principales: Sander, Anna-Lena, Moreira-Soto, Andres, Yordanov, Stoian, Toplak, Ivan, Balboni, Andrea, Ameneiros, Ramón Seage, Corman, Victor, Drosten, Christian, Drexler, Jan Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151638/
https://www.ncbi.nlm.nih.gov/pubmed/35637279
http://dx.doi.org/10.1038/s42003-022-03421-w