Chord: an ensemble machine learning algorithm to identify doublets in single-cell RNA sequencing data

High-throughput single-cell RNA sequencing (scRNA-seq) is a popular method, but it is accompanied by doublet rate problems that disturb the downstream analysis. Several computational approaches have been developed to detect doublets. However, most of these methods may yield satisfactory performance...

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Detalles Bibliográficos
Autores principales: Xiong, Ke-Xu, Zhou, Han-Lin, Lin, Cong, Yin, Jian-Hua, Kristiansen, Karsten, Yang, Huan-Ming, Li, Gui-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151659/
https://www.ncbi.nlm.nih.gov/pubmed/35637301
http://dx.doi.org/10.1038/s42003-022-03476-9