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Chord: an ensemble machine learning algorithm to identify doublets in single-cell RNA sequencing data
High-throughput single-cell RNA sequencing (scRNA-seq) is a popular method, but it is accompanied by doublet rate problems that disturb the downstream analysis. Several computational approaches have been developed to detect doublets. However, most of these methods may yield satisfactory performance...
Autores principales: | Xiong, Ke-Xu, Zhou, Han-Lin, Lin, Cong, Yin, Jian-Hua, Kristiansen, Karsten, Yang, Huan-Ming, Li, Gui-Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151659/ https://www.ncbi.nlm.nih.gov/pubmed/35637301 http://dx.doi.org/10.1038/s42003-022-03476-9 |
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