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The Achilles’ heel of cancer: targeting tumors via lysosome-induced immunogenic cell death

Interest in the lysosome’s potential role in anticancer therapies has recently been appreciated in the field of immuno-oncology. Targeting lysosomes triggers apoptotic pathways, inhibits cytoprotective autophagy, and activates a unique form of apoptosis known as immunogenic cell death (ICD). This me...

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Detalles Bibliográficos
Autores principales: Iulianna, Taritsa, Kuldeep, Neote, Eric, Fossel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151667/
https://www.ncbi.nlm.nih.gov/pubmed/35637197
http://dx.doi.org/10.1038/s41419-022-04912-8