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The Achilles’ heel of cancer: targeting tumors via lysosome-induced immunogenic cell death
Interest in the lysosome’s potential role in anticancer therapies has recently been appreciated in the field of immuno-oncology. Targeting lysosomes triggers apoptotic pathways, inhibits cytoprotective autophagy, and activates a unique form of apoptosis known as immunogenic cell death (ICD). This me...
Autores principales: | Iulianna, Taritsa, Kuldeep, Neote, Eric, Fossel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151667/ https://www.ncbi.nlm.nih.gov/pubmed/35637197 http://dx.doi.org/10.1038/s41419-022-04912-8 |
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