Peripheral monocyte–derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer’s disease

Microglia, the parenchymal tissue macrophages in the brain, surround amyloid plaques in brains of individuals with Alzheimer’s disease (AD) but are ineffective at clearing amyloid to mitigate disease progression. Recent studies in mice indicate that microglia are derived exclusively from primitive y...

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Detalles Bibliográficos
Autores principales: Yan, Ping, Kim, Ki-Wook, Xiao, Qingli, Ma, Xiucui, Czerniewski, Leah R., Liu, Haiyan, Rawnsley, David R., Yan, Yan, Randolph, Gwendalyn J., Epelman, Slava, Lee, Jin-Moo, Diwan, Abhinav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151689/
https://www.ncbi.nlm.nih.gov/pubmed/35511433
http://dx.doi.org/10.1172/JCI152565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151689/
https://www.ncbi.nlm.nih.gov/pubmed/35511433
http://dx.doi.org/10.1172/JCI152565

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