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Transforming dysfunctional CD8(+) T cells into natural controller–like CD8(+) T cells: can TCF-1 be the magic wand?
HIV infection results in defective CD8(+) T cell functions that are incompletely resolved by antiretroviral therapy (ART) except in natural controllers, who have functional CD8(+) T cells associated with viral control. In this issue of the JCI, Perdomo-Celis et al. demonstrated that targeting the Wn...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151690/ https://www.ncbi.nlm.nih.gov/pubmed/35642630 http://dx.doi.org/10.1172/JCI160474 |