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Transforming dysfunctional CD8(+) T cells into natural controller–like CD8(+) T cells: can TCF-1 be the magic wand?

HIV infection results in defective CD8(+) T cell functions that are incompletely resolved by antiretroviral therapy (ART) except in natural controllers, who have functional CD8(+) T cells associated with viral control. In this issue of the JCI, Perdomo-Celis et al. demonstrated that targeting the Wn...

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Detalles Bibliográficos
Autores principales: Takata, Hiroshi, Trautmann, Lydie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151690/
https://www.ncbi.nlm.nih.gov/pubmed/35642630
http://dx.doi.org/10.1172/JCI160474

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