An antibody targeting the N-terminal domain of SARS-CoV-2 disrupts the spike trimer

The protective human antibody response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) focuses on the spike (S) protein, which decorates the virion surface and mediates cell binding and entry. Most SARS-CoV-2 protective antibodies target the receptor-binding domain or a single domina...

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Detalles Bibliográficos
Autores principales: Suryadevara, Naveenchandra, Shiakolas, Andrea R., VanBlargan, Laura A., Binshtein, Elad, Chen, Rita E., Case, James Brett, Kramer, Kevin J., Armstrong, Erica C., Myers, Luke, Trivette, Andrew, Gainza, Christopher, Nargi, Rachel S., Selverian, Christopher N., Davidson, Edgar, Doranz, Benjamin J., Diaz, Summer M., Handal, Laura S., Carnahan, Robert H., Diamond, Michael S., Georgiev, Ivelin S., Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151704/
https://www.ncbi.nlm.nih.gov/pubmed/35472136
http://dx.doi.org/10.1172/JCI159062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151704/
https://www.ncbi.nlm.nih.gov/pubmed/35472136
http://dx.doi.org/10.1172/JCI159062

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