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Experimental solubility and thermodynamic modeling of empagliflozin in supercritical carbon dioxide

The solubility of empagliflozin in supercritical carbon dioxide was measured at temperatures (308 to 338 K) and pressures (12 to 27 MPa), for the first time. The measured solubility in terms of mole faction ranged from 5.14 × 10(–6) to 25.9 × 10(–6). The cross over region was observed at 16.5 MPa. A...

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Detalles Bibliográficos
Autores principales: Sodeifian, Gholamhossein, Garlapati, Chandrasekhar, Razmimanesh, Fariba, Nateghi, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151729/
https://www.ncbi.nlm.nih.gov/pubmed/35637271
http://dx.doi.org/10.1038/s41598-022-12769-2