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Cellular and genetic drivers of RNA editing variation in the human brain

Posttranscriptional adenosine-to-inosine modifications amplify the functionality of RNA molecules in the brain, yet the cellular and genetic regulation of RNA editing is poorly described. We quantify base-specific RNA editing across three major cell populations from the human prefrontal cortex: glut...

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Detalles Bibliográficos
Autores principales: Cuddleston, Winston H., Li, Junhao, Fan, Xuanjia, Kozenkov, Alexey, Lalli, Matthew, Khalique, Shahrukh, Dracheva, Stella, Mukamel, Eran A., Breen, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151768/
https://www.ncbi.nlm.nih.gov/pubmed/35637184
http://dx.doi.org/10.1038/s41467-022-30531-0