Polygenic risk scores to stratify cancer screening should predict mortality not incidence

Population-based cancer screening programs such as mammography or colonscopy generally directed at all healthy individuals in a given age stratum. It has recently been proposed that cancer screening could be restricted to a high-risk subgroup based on polygenic risk scores (PRSs) using panels of sin...

Descripción completa

Detalles Bibliográficos
Autores principales: Vickers, Andrew J., Sud, Amit, Bernstein, Jonine, Houlston, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151796/
https://www.ncbi.nlm.nih.gov/pubmed/35637246
http://dx.doi.org/10.1038/s41698-022-00280-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151796/
https://www.ncbi.nlm.nih.gov/pubmed/35637246
http://dx.doi.org/10.1038/s41698-022-00280-w

Ejemplares similares