A cancer-associated RNA polymerase III identity drives robust transcription and expression of snaR-A noncoding RNA

RNA polymerase III (Pol III) includes two alternate isoforms, defined by mutually exclusive incorporation of subunit POLR3G (RPC7α) or POLR3GL (RPC7β), in mammals. The contributions of POLR3G and POLR3GL to transcription potential has remained poorly defined. Here, we discover that loss of subunit P...

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Detalles Bibliográficos
Autores principales: Van Bortle, Kevin, Marciano, David P., Liu, Qing, Chou, Tristan, Lipchik, Andrew M., Gollapudi, Sanjay, Geller, Benjamin S., Monte, Emma, Kamakaka, Rohinton T., Snyder, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151912/
https://www.ncbi.nlm.nih.gov/pubmed/35637192
http://dx.doi.org/10.1038/s41467-022-30323-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9151912/
https://www.ncbi.nlm.nih.gov/pubmed/35637192
http://dx.doi.org/10.1038/s41467-022-30323-6

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