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Early and Late Transcriptional Changes in Blood, Neural, and Colon Tissues in Rat Models of Stress-Induced and Comorbid Pain Hypersensitivity Reveal Regulatory Roles in Neurological Disease

BACKGROUND: Irritable bowel syndrome (IBS) and temporomandibular disorder (TMD) are two chronic pain conditions that frequently overlap in the same individual, more commonly in women. Stress is a significant risk factor, exacerbating or triggering one or both conditions. However, the mechanisms unde...

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Detalles Bibliográficos
Autores principales: Mocci, Evelina, Goto, Taichi, Chen, Jie, Ament, Seth, Traub, Richard J., Dorsey, Susan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152010/
https://www.ncbi.nlm.nih.gov/pubmed/35655748
http://dx.doi.org/10.3389/fpain.2022.886042