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Cellular and immunometabolic mechanisms of inflammation in depression: Preliminary findings from single cell RNA sequencing and a tribute to Bruce McEwen

Inflammation is associated with symptoms of anhedonia, a core feature of major depression (MD). We have shown that MD patients with high inflammation as measured by plasma C-reactive protein (CRP) and anhedonia display gene signatures of metabolic reprograming (e.g., shift to glycolysis) necessary t...

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Detalles Bibliográficos
Autores principales: Bekhbat, Mandakh, Ulukaya, G. Bengü, Bhasin, Manoj K., Felger, Jennifer C., Miller, Andrew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152104/
https://www.ncbi.nlm.nih.gov/pubmed/35655933
http://dx.doi.org/10.1016/j.ynstr.2022.100462