MET∆14 promotes a ligand-dependent, AKT-driven invasive growth

MET is an oncogene encoding the tyrosine kinase receptor for hepatocyte growth factor (HGF). Upon ligand binding, MET activates multiple signal transducers, including PI3K/AKT, STAT3, and MAPK. When mutated or amplified, MET becomes a “driver” for the onset and progression of cancer. The most freque...

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Detalles Bibliográficos
Autores principales: Cerqua, Marina, Botti, Orsola, Arigoni, Maddalena, Gioelli, Noemi, Serini, Guido, Calogero, Raffaele, Boccaccio, Carla, Comoglio, Paolo M, Altintas, Dogus M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152130/
https://www.ncbi.nlm.nih.gov/pubmed/35636967
http://dx.doi.org/10.26508/lsa.202201409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152130/
https://www.ncbi.nlm.nih.gov/pubmed/35636967
http://dx.doi.org/10.26508/lsa.202201409

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