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Axonal transport of Hrs is activity dependent and facilitates synaptic vesicle protein degradation

Turnover of synaptic vesicle (SV) proteins is vital for the maintenance of healthy and functional synapses. SV protein turnover is driven by neuronal activity in an endosomal sorting complex required for transport (ESCRT)-dependent manner. Here, we characterize a critical step in this process: axona...

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Detalles Bibliográficos
Autores principales: Birdsall, Veronica, Kirwan, Konner, Zhu, Mei, Imoto, Yuuta, Wilson, Scott M, Watanabe, Shigeki, Waites, Clarissa L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152131/
https://www.ncbi.nlm.nih.gov/pubmed/35636965
http://dx.doi.org/10.26508/lsa.202000745