Rare Alleles and Signatures of Selection on the Immunodominant Domains of Pfs230 and Pfs48/45 in Malaria Parasites From Western Kenya

Background: Malaria elimination and eradication efforts can be advanced by including transmission-blocking or reducing vaccines (TBVs) alongside existing interventions. Key transmission-blocking vaccine candidates, such as Pfs230 domain one and Pfs48/45 domain 3, should be genetically stable to avoi...

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Detalles Bibliográficos
Autores principales: Ochwedo, Kevin O., Ariri, Fredrick O., Otambo, Wilfred O., Magomere, Edwin O., Debrah, Isaiah, Onyango, Shirley A., Orondo, Pauline W., Atieli, Harrysone E., Ogolla, Sidney O., Otieno, Antony C. A., Mukabana, Wolfgang R., Githeko, Andrew K., Lee, Ming-Chieh, Yan, Guiyun, Zhong, Daibin, Kazura, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152164/
https://www.ncbi.nlm.nih.gov/pubmed/35656326
http://dx.doi.org/10.3389/fgene.2022.867906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152164/
https://www.ncbi.nlm.nih.gov/pubmed/35656326
http://dx.doi.org/10.3389/fgene.2022.867906

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