Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium

Major Histocompatibility Complex (MHC)-I and -II genes are upregulated in intestinal epithelial cells (IECs) during active inflammatory bowel diseases (IBD), but little is known about how IBD-relevant pro-inflammatory signals and IBD drugs can regulate their expression. We have previously shown that...

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Detalles Bibliográficos
Autores principales: Gopalakrishnan, Shreya, Hansen, Marianne Doré, Skovdahl, Helene Kolstad, Roseth, Ingrid Aass, van Beelen Granlund, Atle, Østvik, Ann Elisabet, Bakke, Ingunn, Sandvik, Arne Kristian, Bruland, Torunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152176/
https://www.ncbi.nlm.nih.gov/pubmed/35655783
http://dx.doi.org/10.3389/fimmu.2022.882277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152176/
https://www.ncbi.nlm.nih.gov/pubmed/35655783
http://dx.doi.org/10.3389/fimmu.2022.882277

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