Inflammasome assembly is required for intracellular formation of β2-microglobulin amyloid fibrils, leading to IL-1β secretion

INTRODUCTION: Dialysis-related amyloidosis (DRA) caused by β2-microgloblin (B2M) fibrils is a serious complication for patients with kidney failure on long-term dialysis. Deposition of B2M amyloid fibrils is thought to be due not only to serum extracellular B2M but also to infiltrating inflammatory...

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Detalles Bibliográficos
Autores principales: Kaneko, Naoe, Mori, Wakako, Kurata, Mie, Yamamoto, Toshihiro, Zako, Tamotsu, Masumoto, Junya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152197/
https://www.ncbi.nlm.nih.gov/pubmed/35615856
http://dx.doi.org/10.1177/03946320221104554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152197/
https://www.ncbi.nlm.nih.gov/pubmed/35615856
http://dx.doi.org/10.1177/03946320221104554

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