Sleep and Late-Onset Alzheimer’s Disease: Shared Genetic Risk Factors, Drug Targets, Molecular Mechanisms, and Causal Effects

Late-onset Alzheimer’s disease (AD) is associated with sleep-related phenotypes (SRPs). The fact that whether they share a common genetic etiology remains largely unknown. We explored the shared genetics and causality between AD and SRPs by using high-definition likelihood (HDL), cross-phenotype ass...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Dongze, Wang, Xinpei, Huang, Tao, Jia, Jinzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152224/
https://www.ncbi.nlm.nih.gov/pubmed/35656316
http://dx.doi.org/10.3389/fgene.2022.794202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152224/
https://www.ncbi.nlm.nih.gov/pubmed/35656316
http://dx.doi.org/10.3389/fgene.2022.794202

Ejemplares similares