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Hepatic Organoid-Based High-Content Imaging Boosts Evaluation of Stereoisomerism-Dependent Hepatotoxicity of Stilbenes in Herbal Medicines

The complexity of chemical components of herbal medicines often causes great barriers to toxicity research. In our previous study, we have found the critical divergent hepatotoxic potential of a pair of stilbene isomers in a famous traditional Chinese herb, Polygonum multiflorum (Heshouwu in Chinese...

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Detalles Bibliográficos
Autores principales: Liu, Juan, Li, Tingting, Li, Ruihong, Wang, Jie, Li, Pengyan, Niu, Ming, Zhang, Le, Li, Chunyu, Wang, Tao, Xiao, Xiaohe, Wang, Jia-bo, Wang, Yunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152290/
https://www.ncbi.nlm.nih.gov/pubmed/35656304
http://dx.doi.org/10.3389/fphar.2022.862830